Thermal response of multi-layer UV crosslinked PEGDA hydrogels

Poly(ethylene glycol) diacrylate (PEGDA) hydrogels are ubiquitously used in a wide variety of applications tissue engineering. In this study, the thermal response multi-layered PEGDA was investigated under various conditions temperature-controlled environments (8, 20, 37, and 45 °C) through gravimetric volumetric methods. These were produced using computer-controlled projection lithography compared to monolithic fabricated bulk photo-crosslinking. It observed that volume increased about 10% at temperature 8 °C, while their decreased by 8% 12% when stored 37 °C respectively. hydrogel also showed an anisotropic characteristic where axial dimensional change 43% higher than lateral dimension. This finding is critical inform design fabrication compensate for changes during application different temperatures.